This episode follows the aftermath of Olivia's capture in the previous episode, and subsequent efforts to identify and apprehend her kidnappers. Along with a double agent, Olivia's investigation is hampered by the appearance of Sanford Harris, an old adversary hired to audit Fringe Division.
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When Olivia confronted Loeb after he kidnapped her and she escaped, he claimed that they were actually trying to save her.
The Observer can be seen at Harvard walking across down the sidewalk as Peter and Walter meet Olivia at her car.
There is a poster for 'The Colds' on the bar wall behind Olivia in 'Safe' when Peter shows her a card trick. This is a reference to the supersized common cold virus in 'Bound'
At the end of 'Bound' Olivia falls asleep reading a book to Ella entitled "What's that Noise?", referring to the text in the killer program in 'The No-Brainer'.
- Project 1087 - Exploration 1 -
First an overgrown protozoan wrapped 'round the heart; now a mammoth virus grown in the belly. How difficult it proves to separate myth from fact, and fact from myth! Gigantism abounds in legend. The giant Ouranos begat Cronos, also a giant; and from his belly burst the Olympians, themselves giants in the eyes of men. And likewise did Buri beget Bor who begat Wotan...
Straightway the Allfather cast the serpent into the deep sea, where he lies about all the land; and this serpent grew so greatly that he lies in the midst of the ocean encompassing all the land, and bites upon his own tail.
So said Snorri of the overgrown serpent. Always giants within giants within giants -- of course! This gorgeous creature is not, in fact, a giant virus. The rhinovirus takes the form of an icosahedron, not a slug. No, she is a gigantic human cell -- from Dr. Kinberg's own intestinal walls -- mercilessly overtaken and supersized by the giant virus that infected her.
SUPERSIZED! A new word in my lexicon. Such a brilliant concept: to order a tasty meal and, with one simple command, expand it in all dimensions. The wonder and horror of it; for how could I not observe the astounding synecdoche between the consumers and the consumed? Giants within giants again. To what other purposes might this remarkable technique be applied? Squashes that will squash the county fair records? In class mammalia, order rodentia, the rise of the ROUS's? Even we hominids might take part. More than a few females might wish to grow their assets; men, too.
But, caution is essential -- for the pace of protein production must have been astonishingly rapid to sustain both cellular growth and... oh, my. This volume of cytoplasm could only have one purpose: large-scale viral production. Within this slug-like sack there could be millions of copies of its pathogenic parent. Extra care must be taken to contain her. No more afternoon walks for Betsy, I suppose. Wait... where did I see her last?
The two sides of the war, the Blueverse and the Redverse, become apparent in "Over There (Part 1)".